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pentobarbital will decrease the level or result of estropipate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.pentobarbital will lessen the level or outcome of dasatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.Barbiturates are metabolized principally with the hepatic microsom